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dc.contributor.authorKeryer, Gfr_FR
dc.contributor.authorBailly, Efr_FR
dc.date.accessioned2013-02-15T11:59:58Z
dc.date.available2013-02-15T11:59:58Z
dc.date.issued1994fr_FR
dc.identifier.citationKeryer, G ; Bailly, E, Spécificité de l'action des protéine kinases et phosphatases dans la cellule, Med Sci (Paris), 1994, Vol. 10, N° 4; p.408-16fr_FR
dc.identifier.issn1958-5381fr_FR
dc.identifier.urihttp://hdl.handle.net/10608/2630
dc.description.abstractThe broad substrate specificity of most of the kinases and phosphatases, the enzymes involved in the reversible phosphorylation of proteins, must be restricted in vivo to further ensure an efficient and precise signaling. Here we review recent evidence indicating that at least two families of kinases and one family of phosphatases use a similar strategy to their catalytic subunit towards their specific substrates. The targeting subunit of these modular enzymes could direct the catalytic subunit to their appropriate target locus. The centrosome, the organiser of cell microtubules, is chosen to illustrate a privileged target locus for several kinases and phosphatases, using such a targeting subunit strategy.fr
dc.language.isofrfr_FR
dc.publisherJohn Libbey Eurotext, Montrougefr_FR
dc.rightsArticle en libre accèsfr
dc.rightsMédecine/Sciences - Inserm - SRMSfr
dc.sourceM/S. Médecine sciences [revue papier, ISSN : 0767-0974], 1994, Vol. 10, N° 4; p.408-16fr_FR
dc.titleSpécificité de l'action des protéine kinases et phosphatases dans la cellulefr
dc.typeArticlefr_FR
dc.identifier.doi10.4267/10608/2630


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