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Chroniques génomiques : Un chapeau pour mon repas ?
(Éditions EDK/Groupe EDP Sciences, 2013)
After clearing many hurdles, gene therapy is now reaching the commercialization stage and can be expected to make a modest but real contribution to treatment in the near future.
Chroniques génomiques - Henrietta Lacks et les cellules HeLa : Les leçons d’une histoire
(Éditions EDK/Groupe EDP Sciences, 2013)
An exceptional arrangement concluded for access to the HeLa cell line sequence highlights the problems involved in studies on « old » samples obtained before ethical and privacy safeguards were in place.
Chroniques génomiques : En route vers l’enfant parfait !
(Éditions EDK/Groupe EDP Sciences, 2013)
Sequencing technology now makes possible non-invasive prenatal diagnosis, and may soon allow detailed examination of the embryo genome from analysis of a single cell. These positive developments that avoid potentially ...
Chroniques génomiques : Myriad Genetics L’arme du secret
(Éditions EDK/Groupe EDP Sciences, 2013)
Chroniques génomiques : La génétique du trou de souris
(Éditions EDK/Groupe EDP Sciences, 2013)
The Oldfield mouse and the Deer mouse build very different burrows in nature and also in the laboratory. This behaviour is innate and, in a series of beautiful experiments making use of new generation sequencing for genetic ...
Chroniques génomiques : Épigénétique et résilience
(Éditions EDK/Groupe EDP Sciences, 2013)
The likelihood of adult psychiatric problems is increased by childhood trauma, particularly so in carriers of certain alleles of certain genes. I discuss here a recent paper that sheds light on the mechanism of this effect, ...
Chroniques génomiques : Un hasard dirigé
(Éditions EDK/Groupe EDP Sciences, 2013)
Whole-genome sequencing of monozygotic twin pairs and of their parents brings new and surprising insights into the rate and distribution of de novo mutations.