Chroniques génomiques - Gènes et longévité : nouvelles données, nouvelles controverses

Abstract

Analysis of a huge human pedigree constructed using public genealogy databases indicates that the heritability of longevity is probably lower than previously accepted (0.10 to 0.15 instead of 0.25 to 0.30). This makes the search for “longevity genes” even harder than expected; nevertheless, some significant results emerge and may eventually, after confirmation and extension, provide useful insights.