dc.contributor.author | Liu, Wen-Juan | - |
dc.contributor.author | Wang, Xiao-Dan | - |
dc.contributor.author | Wu, Wei | - |
dc.contributor.author | Huang, Xiao | - |
dc.date.accessioned | 2019-11-05T12:52:00Z | |
dc.date.available | 2019-11-05T12:52:00Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Liu, Wen-Juan ; Wang, Xiao-Dan ; Wu, Wei ; Huang, Xiao ; Relationship between depression and blood cytokine levels in lung cancer patients, Med Sci (Paris), , Vol. 34, N° HS ; p. 113-115 ; DOI : 10.1051/medsci/201834f119 | |
dc.identifier.issn | 1958-5381 | |
dc.identifier.uri | http://hdl.handle.net/10608/9996 | |
dc.description.abstract | Objective: To study the correlation between depression and blood cytokine levels in lung cancer patients. Methods: 92 patients with advanced lung cancer were evaluated for depression using the scoring index of depression self-rating scale. Lack of depression (n=24), mild depression (n=45), and moderate depression (n=23) were found in the cohort. Meanwhile, 40 healthy subjects were selected as the control group. The levels of IL-10, IL-6, IL-8, and TNF-α in each group were detected by sandwich enzyme-linked immunosorbent assays, and their correlation with the degree of depression was analyzed. Results: The levels of IL-10, IL-6, IL-8, and TNF-α were all higher than those in the control group (P<0.05). Moreover, the depression statuses of patients with lung cancer were positively correlated with IL-10, IL-6, and TNF-α levels (r = 0.705, 0.301, and 0.446, P<0.01); however, the level of IL-8 was not relevant (r=0.136, p>0.05). Conclusion: Serum levels of IL-10, IL-6, and TNF-α are associated with depression scoring in patients with lung cancer. | en |
dc.language.iso | en | |
dc.publisher | EDP Sciences | |
dc.rights | Article en libre accès | fr |
dc.rights | Médecine/Sciences - Inserm - SRMS | fr |
dc.source | M/S. Médecine sciences [ISSN papier : 0767-0974 ; ISSN numérique : 1958-5381], , Vol. 34, N° HS; p. 113-115 | |
dc.title | Relationship between depression and blood cytokine levels in lung cancer patients | en |
dc.type | Article | |
dc.contributor.affiliation | MD, Department of Psychological Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai (200032), China | |
dc.contributor.affiliation | Department of Respiratory Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | |
dc.contributor.affiliation | Department of Pharmacy, Zhongshan Hospital, Fudan University, Shangai 200032, China | |
dc.identifier.doi | 10.1051/medsci/201834f119 | |