Parcourir MS 1993 par date de publication
Voici les éléments 1-20 de 260
-
Structure et fonction du récepteur ß-3 adrénergique
(John Libbey Eurotext, Montrouge, 1993)Long-term treatment of obese animals with lipolytic selective agents induces weight loss and restores insulin sensitivity. Such effects appear to be mediated by a novel catecholamine receptor - the beta 3-adrenergic receptor ... -
Origine et progression des tumeurs épithéliales : vers les mécanismes cellulaires et moléculaires
(John Libbey Eurotext, Montrouge, 1993) -
Erythroenzymopathies : modèle d'études coordonnées par biochimie et biologie moléculaire.
(John Libbey Eurotext, Montrouge, 1993)Since the discovery of glucose 6-phosphate dehydrogenase and pyruvate kinase deficiencies, many other erythrocyte enzymes abnormalities have been found. Most enzyme deficiencies from the Embden-Meyerhof pathway, pentose-phosphate ... -
L'origine et l'évolution de la reproduction animale
(John Libbey Eurotext, Montrouge, 1993)Sexually reproducing organisms have alternating haploid and diploid phases. Each phase is connected to the other through meiosis and fertilization or conjugation. This article provides a tentative explanation for several ... -
La régulation pluri-hormonale intégrée des fonctions rénales
(John Libbey Eurotext, Montrouge, 1993)The kidney is the main organ regulating the composition of the body fluids. A considerable number of hormones controls the activity of the renal cells to maintain the equilibrium of the hydromineral balance. It becomes ... -
Bases moléculaires du transport vers les lysosomes
(John Libbey Eurotext, Montrouge, 1993)In high eucaryotes, the mannose 6-phosphate receptors (MPRs) are essential components that allow proper targeting of lysosomal enzymes to lysosomes. Two mannose 6-phosphate receptors have been characterized. The first has ... -
Vers une description du mécanisme d'assemblage du fuseau mitotique à l'échelle moléculaire
(John Libbey Eurotext, Montrouge, 1993)Morphogenesis of the mitotic spindle raises original questions because it is a transient, highly dynamic structure. The reorganization of microtubules from a radial array in interphase into a bipolar spindle during mitosis, ... -
Les premiers pas de la faculté de médecine de l'université de Montréal
(John Libbey Eurotext, Montrouge, 1993) -
La protéine Tat du VIH : cible potentielle en chimiothérapie anti-rétrovirale
(John Libbey Eurotext, Montrouge, 1993)The human immunodeficiency virus (HIV) encodes numerous regulatory proteins among which Tat and Rev are essential for virus replication. These proteins control HIV gene expression through interaction with specific regions ... -
AP-HP Groupe d'études et de recherche sur le médicament (GERMED) : les anticorps monoclonaux – nouvelles brèves
(John Libbery Eurotext, MontrougeArticle en libre accès, 1993) -
Syndrome de Cushing induit par le GIP : expression clinique d'un récepteur ectopique
(John Libbey Eurotext, Montrouge, 1993)The pathophysiology of non-ACTH-dependent adrenal nodular hyperplasia and tumors resulting in Cushing's syndrome is still largely unknown. Previous in vitro studies have demonstrated the presence of ectopic (mostly ... -
Les domaines de liaison à l'ADN des facteurs de transcription eucaryotes.
(John Libbey Eurotext, Montrouge, 1993)Most of transcription factors recognize specific DNA sequences through small, discrete domains. In some cases, these domains can be interchanged between proteins showing that they are independently folded units. Mutational ... -
Le complexe majeur d'histocompatibilité : recombinaison, pressions sélectives et évolution.
(John Libbey Eurotext, Montrouge, 1993)Genes coding for the major histocompatibility complex (MHC) class I and class II molecules belong to relatively large multigene families. Most of these genes have been involved in immunological phenomena such as graft ... -
Une interprétation évolutive de la gamétogenèse animale
(John Libbey Eurotext, Montrouge, 1993)Motility is an essential property of all animal germ cells. Gametogenesis can be divided into three main phases with respect to germ cell motility. Primordial germ cells migrate into the gonadal rudiments. A long captive ... -
Retard de croissance intra-utérin et déficit en néphrons
(John Libbey Eurotext, Montrouge, 1993)The number of nephrons at birth is normally quite fixed in any species. Severe renal hypoplasia is readily detected because of functional insufficiency, but moderate inborn nephron deficits may exist, yeat remain undetected. ... -
Cycline-A et Cancer
(John Libbey Eurotext, Montrouge, 1993)Cyclin A is a multifunctional protein. It associates to p34cdk2 kinase and is thus involved in the G2/M the E2F transcription factor, the p33cdc2 kinase, and the Rb(p107) homologue. The modified expression of cyclin A in ... -
La segmentation du mésoderme chez les vertébrés
(John Libbey Eurotext, Montrouge, 1993) -
Quel avenir pour la souris mdx comme modèle de la dystrophie musculaire de Duchenne ?
(John Libbey Eurotext, Montrouge, 1993)Duchenne muscular dystrophy (DMD) is a severe form of an X-linked muscular dystrophy characterized by a progressive weakness of the striated muscles. Many animal models of DMD have been extensively studied for the last ... -
Pathologie thyroïdienne morphologique radio-induite par de faibles doses d'irradiation cervicale : apport d'une enquête épidémiologique de cohorte.
(John Libbery Eurotext, Montrouge, 1993)Thyroid morphological exploration was carried out on 396 patients who were recalled because their thyroid gland had been exposed during angiomas irradiation in childhood 11-43 years before (median, 22 years). Among these ... -
Bréfeldine A, protéines-G et transports membranaires golgiens.
(John Libbey Eurotext, Montrouge, 1993)This review has attempted to provide a synthesis of the growing number of observations on the effects of the fungal metabolite brefeldin A. This drug dramatically alters the morphology of the Golgi complex and the return ...