Chroniques génomiques - Les sénolytiques contre la Covid-19 ?

Jordan, Bertrand

doi:10.1051/medsci/2021161

dc.contributor.author	Jordan, Bertrand	-
dc.date.accessioned	2022-10-17T15:09:03Z
dc.date.available	2022-10-17T15:09:03Z
dc.date.issued	2021
dc.identifier.citation	Jordan, Bertrand ; Les sénolytiques contre la Covid-19 ? : Chroniques génomiques, Med Sci (Paris), Vol. 37, N° 11 ; p. 1062-1065 ; DOI : 10.1051/medsci/2021161
dc.identifier.issn	1958-5381
dc.identifier.uri	http://hdl.handle.net/10608/11942
dc.description.abstract	The elimination of some senescent cells by « senolytic » compounds can greatly improve the health of aged mice and in some cases reverse the effects of aging. Using a microbial exposure system that closely models coronavirus infection, it is possible to largely protect old mice from the effects of viral infection. This immediately suggests clinical application of the approach, and is the aim of ongoing phase II clinical trials in Covid-19 patients.	en
dc.language.iso	fr
dc.publisher	EDP Sciences
dc.relation.ispartof	Forum
dc.rights	Article en libre accès - License CC BY 4.0	fr
dc.rights	Médecine/Sciences - Inserm - SRMS	fr
dc.rights.uri	http://creativecommons.org/licenses/by/4.0
dc.source	M/S. Médecine sciences [ISSN papier : 0767-0974 ; ISSN numérique : 1958-5381], Vol. 37, N° 11; p. 1062-1065
dc.subject.mesh	Vieillissement	fr
dc.subject.mesh	Animaux	fr
dc.subject.mesh	COVID-19	fr
dc.subject.mesh	Vieillissement de la cellule	fr
dc.subject.mesh	Essais cliniques de phase II comme sujet	fr
dc.subject.mesh	Humains	fr
dc.subject.mesh	Souris	fr
dc.subject.mesh	SARS-CoV-2	fr
dc.subject.mesh	Sénothérapie	fr
dc.subject.mesh	effets des médicaments et substances chimiques	fr
dc.subject.mesh	traitement médicamenteux	fr
dc.title	Chroniques génomiques - Les sénolytiques contre la Covid-19 ?	fr
dc.title.alternative	Senolytics against Covid-19?	en
dc.type	Article
dc.contributor.affiliation	ADÉS (Anthropologie bioculturelle, droit, éthique et santé) UMR CNRS 7268, Aix Marseille université, Établissement français du sang. CoReBio PACA, case 901, Parc scientifique de Luminy , 13288 Marseille Cedex 09 , France
dc.identifier.doi	10.1051/medsci/2021161
dc.identifier.pmid	34851287