Chroniques génomiques - Mutations somatiques et longévité
Résumé
New approaches allow precise measurement of somatic mutations in tissues. Applied to a diverse set of mammals, these methods show that somatic mutation load increases with age (as expected) but reaches similar levels near the end of life for animals with extremely different longevity. This is an important result that has many repercussions on concepts of aging and of evolution of longevity.
Pour citer ce document
Jordan, Bertrand ; Mutations somatiques et longévité : Chroniques génomiques, Med Sci (Paris), Vol. 38, N° 8-9 ; p. 723-725 ; DOI : 10.1051/medsci/2022098