Chroniques génomiques - Taille à l’âge adulte : une myriade de locus
Résumé
The combination of 281 GWAS studies for adult height leads to the identification of 12,111 SNP in 7,209 loci that together account for essentially all SNP heritability for this trait: there is no longer any significant “missing heritability”, and these loci appear to be functionally relevant. This work is a model for future studies on the genetic determinants of complex diseases.
Pour citer ce document
Jordan, Bertrand ; Taille à l’âge adulte : une myriade de locus : Chroniques génomiques, Med Sci (Paris), Vol. 39, N° 1 ; p. 83-86 ; DOI : 10.1051/medsci/2022187