Afficher la notice abrégée

dc.contributor.authorRabenandrasana, C.fr_FR
dc.contributor.authorRamsohoye, P.fr_FR
dc.date.accessioned2013-02-15T11:58:37Z
dc.date.available2013-02-15T11:58:37Z
dc.date.issued1994fr_FR
dc.identifier.citationRabenandrasana, C. ; Ramsohoye, P., La clusterine : une nouvelle glycoprotéine protectrice de l'intégrité cellulaire ?, Med Sci (Paris), 1994, Vol. 10, N° 1; p.12-20fr_FR
dc.identifier.issn1958-5381fr_FR
dc.identifier.urihttp://hdl.handle.net/10608/2476
dc.description.abstractClusterin, a heterodimeric glycoprotein has emerged in scientific reports from disparate fields of cell biology. This molecule is widely expressed in mammalian species. Clusterin has been associated to physiological functions including cell-cell interactions, immune defense secretion and lipid transport. A marked induction of clusterin level has been reported during neurodegenerative diseases and renal injuries. The measurement of clusterin could be used as a clinical marker of these pathologies. Its ability to inhibit complement mediated lysis and its lipid-binding capacity confer to clusterin qualities for cellular membrane protection. This molecule could serve as a protective mechanism against immunological activation fo complement system occurring after tissue injury and to maintain cell membrane integrity in a physiological state against noxious hydrophobic molecules.fr
dc.language.isofrfr_FR
dc.publisherJohn Libbey Eurotext, Montrougefr_FR
dc.rightsArticle en libre accèsfr
dc.rightsMédecine/Sciences - Inserm - SRMSfr
dc.sourceM/S. Médecine sciences [revue papier, ISSN : 0767-0974], 1994, Vol. 10, N° 1; p.12-20fr_FR
dc.titleLa clusterine : une nouvelle glycoprotéine protectrice de l'intégrité cellulaire ?fr
dc.typeArticlefr_FR
dc.identifier.doi10.4267/10608/2476


Fichier(s) constituant ce document

Thumbnail
Thumbnail

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée