Explorer de nouveaux domaines SH2/SH3
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SH2 domains have been found in a wide range of non receptor tyrosine kinases, such as GAP, phospholipase Cy-1 and the non catalytic phosphorylated regions in growth factor tyrosine kinases. A better understanding of SH2 containing proteins should increase knowledge of the mechanism by which external signalling events effect the growth and differentiation of cells. Reagents with SH2 domains offer a new approach to study fundamental questions linked to signal transduction.
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Moore, B. ; Seroussi, G. ; Jochim, B., Explorer de nouveaux domaines SH2/SH3, Med Sci (Paris), 1993, Vol. 9, N° 6-7; p.788-790