Chroniques génomiques : Épigénétique et résilience
Résumé
The likelihood of adult psychiatric problems is increased by childhood trauma, particularly so in carriers of certain alleles of certain genes. I discuss here a recent paper that sheds light on the mechanism of this effect, showing that specific demethylation occurring at the time of the initial trauma persists at adulthood and induces an increased reactivity to stress.
Pour citer ce document
Jordan, Bertrand ; Chroniques génomiques : Épigénétique et résilience, Med Sci (Paris), 2013, Vol. 29, N° 3 ; p. 325-328 ; DOI : 10.1051/medsci/2013293020