Chroniques génomiques - Thérapie génique germinale, le retour ?
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The recent development of a powerful and flexible genome editing technique (the CRISP-cas9 method) accelerates tremendously the production of animal models and will significantly enhance the perspectives of (somatic) gene therapy. However, it also raises a real possibility of germline modifications in humans, with therapeutic aims or for “improvement”: this raises thorny ethical questions that are no longer theoretical (as in the 1990s) but will have to be faced in the very near future.
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Jordan, Bertrand ; Thérapie génique germinale, le retour ? : Chroniques génomiques, Med Sci (Paris), 2015, Vol. 31, N° 6-7 ; p. 691-695 ; DOI : 10.1051/medsci/20153106025