Parcourir MS 2018 Focus Issue1 par auteur "Dang, Ningning"

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Knock-down of filaggrin influences the mitogen-activated protein kinases signaling pathway in normal human epidermal keratinocytes

Wang, Shumei; Qiu, Liyun; Meng, Xianguang; Dang, Ningning (EDP Sciences, 2018)

Background: Filaggrin is an essential structural protein of the stratum corneum binding to the keratin intermediate filaments to form a dense protein-lipid matrix. However, the function of filaggrin in epidermal terminal ...
NPS - 2143 (hydrochloride) inhibits melanoma cancer cell proliferation and induces autophagy and apoptosis

Wang, Shumei; Qiu, Liyun; Song, Haiyan; Dang, Ningning (EDP Sciences, 2018)

Melanoma is a common and aggressive skin cancer caused by the oncogenic transformation of melanocytes. NPS-2143 (hydrochloride) is a calcification drug that acts as an antagonist of the calcium-sensing receptor (CaSR) and ...