Recherche
Voici les éléments 1-6 de 6
Chroniques génomiques - L’invasion des tests non invasifs
(EDP Sciences, 2014)
Non-invasive prenatal testing is becoming commonplace, but, in addition, other tests using only a blood sample are being developed and will have a significant impact, notably in oncology.
Chroniques génomiques - Hétérogénéité des tumeurs : l’apport du séquençage sur cellules individuelles
(Éditions EDK, Groupe EDP Sciences, 2014)
The heterogeneity of tumours is now beginning to be documented precisely by single-cell new-generation sequencing. Recently published results on breast tumours show that each of the cells analysed displays a unique pattern ...
Chroniques Génomiques - Les chimères du dépistage
(Éditions EDK, Groupe EDP Sciences, 2017)
The use of circulating tumour DNA to screen for cancer in asymptomatic individuals is the goal of Grail, initially set up by Illumina. This company is now raising a large amount of capital to develop this project on a much ...
Chroniques génomiques - Le monde caché des clones mutants dans les tissus normaux
(EDP Sciences, 2019)
Careful sequencing studies on small samples of normal oesophageal epithelium reveal the presence of very abundant cellular clones harbouring mutations in known cancer genes (and elsewhere). The number and size of these ...
Chroniques génomiques - Un cadeau empoisonné
(EDP Sciences, 2020)
GWAS analysis of severe Covid patients implicates a major locus on chromosome 3. The corresponding 50 kb segment appears to originate from Neanderthal/Sapiens crossings, raising interesting evolutionary questions.
Chroniques génomiques - Scores polygéniques et risque de cancer
(EDP Sciences, 2020)
Risk assessment for a cancer type with moderate heritability can be accurately performed using a relatively small number of SNPs detected by GWAS analyses to calculate a polygenic risk score (PRS) that has definite clinical ...