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Chroniques génomiques - Thérapie génique germinale, le retour ?
(Éditions EDK, Groupe EDP Sciences, 2015)
The recent development of a powerful and flexible genome editing technique (the CRISP-cas9 method) accelerates tremendously the production of animal models and will significantly enhance the perspectives of (somatic) gene ...
Chroniques génomiques - Dépistage du cancer : les promesses illusoires de Pathway Genomics
(Éditions EDK, Groupe EDP Sciences, 2015)
The “liquid biopsy” approach shows promise for characterization and monitoring of cancer during treatment; however a blood-based detection test for “high-risk” but asymptomatic individuals, recently introduced by Pathway ...
Les années 2000
(Éditions EDK, Groupe EDP Sciences, 2015)
Chroniques génomiques - CRISPR-Cas9, une nouvelle donne pour la thérapie génique
(Éditions EDK, Groupe EDP Sciences, 2015)
Targeted modification of genes (“gene editing”) is made much easier by the recently developed CRISPR-Cas9 system. This has raised alarm about possible uses of this technology for germline modification of the human genome; ...
Chroniques génomiques - Séquencer les bébés ?
(Éditions EDK, Groupe EDP Sciences, 2015)
An extension of newborn screening to genome sequencing is now feasible but raises a number of scientific, organisational and ethical issues. This is being explored in discussions and in several funded trials, in order to ...
Les années 2010
(Éditions EDK, Groupe EDP Sciences, 2015)
Chroniques génomiques - Biopsies liquides, une révolution en cancérologie ?
(Éditions EDK, Groupe EDP Sciences, 2015)
The detection and analysis of circulating tumour DNA and/or circulating tumour cells in the blood of cancer patients open new possibilities for cancer characterisation and management. The approach has generated much ...
Chroniques génomiques - Encore le « gène du crime » ?
(Éditions EDK, Groupe EDP Sciences, 2015)
A new genetic study focussing on the degree of violence in criminals and using both candidate gene and GWAS approaches finds statistically significant associations of extreme violent behaviour with low activity alleles of ...
Chroniques génomiques - Des résultats tout à fait inattendus
(Éditions EDK, Groupe EDP Sciences, 2015)
There are now a number of cases in which non-invasive prenatal testing (NIPT) has detected signs of cancer in pregnant women. These unexpected findings raise a number of difficult questions regarding their communication ...
Chroniques génomiques - Du bon usage d’un test non invasif
(Éditions EDK, Groupe EDP Sciences, 2015)